Development and Validation of HPTLC Method for Estimation of Carbamazepine in Formulations and Its <i>In Vitro</i> Release Study

<table class="table-group" id="tab7"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Formulation</td><td align="center">Label claim</td><td align="center">Amount found (mean <svg height="9.3249998" id="M112" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 10.825 9.3249998" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.325)">
<g transform="translate(72,-64.54)">
<text transform="matrix(1,0,0,-1,-71.95,65.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">±</tspan>
</text>
</g>
</g>
</svg> SD)</td><td align="center">%RSD</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">F1</td><td align="center">1 mg/ml</td><td align="center">1.09 <svg height="9.3249998" id="M113" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 10.825 9.3249998" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.325)">
<g transform="translate(72,-64.54)">
<text transform="matrix(1,0,0,-1,-71.95,65.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">±</tspan>
</text>
</g>
</g>
</svg> 0.21 mg/ml</td><td align="center">1.3</td></tr><tr><td align="left">F2</td><td align="center">1 mg/ml</td><td align="center">1.0 <svg height="9.3249998" id="M114" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 10.825 9.3249998" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.325)">
<g transform="translate(72,-64.54)">
<text transform="matrix(1,0,0,-1,-71.95,65.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">±</tspan>
</text>
</g>
</g>
</svg> 0.26 mg/ml</td><td align="center">1.2</td></tr><tr><td align="left">F3</td><td align="center">1 mg/ml</td><td align="center">1.17 <svg height="9.3249998" id="M115" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 10.825 9.3249998" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.325)">
<g transform="translate(72,-64.54)">
<text transform="matrix(1,0,0,-1,-71.95,65.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">±</tspan>
</text>
</g>
</g>
</svg> 0.15 mg/ml</td><td align="center">1.1</td></tr><tr><td align="left">Tablets</td><td align="center">100 mg/tablet</td><td align="center">99.35 <svg height="9.3249998" id="M116" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 10.825 9.3249998" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.325)">
<g transform="translate(72,-64.54)">
<text transform="matrix(1,0,0,-1,-71.95,65.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">±</tspan>
</text>
</g>
</g>
</svg> 1.49 mg/tablet</td><td align="center">1.3</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Content of Carbamazepine in various formulations.

Chromatography Research International

tab7

Table 7

Table 7: Development and Validation of HPTLC Method for Estimation of Carbamazepine in Formulations and Its <i>In Vitro</i> Release Study 

Chromatography Research International

Development and Validation of HPTLC Method for Estimation of Carbamazepine in Formulations and Its In Vitro Release Study

Table 7