Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist
Figure 3
Typical method development RP-LC chromatograms of different stationary phases. (a) Hypersil BDS (250 × 4.6 mm, 5 μ) and (b) synergi Max RP (250 × 4.6 mm, 4 μ), (c) Cyano (250 × 4.6 mm, 5 μ).
