Research Article
Pharmacokinetics of Single-Dose and Multi-Dose of Lovastatin/Niacin ER Tablet in Healthy Volunteers
Table 2
Intra- and interrun precision and accuracy of determination of NA, NAM, NUA, and lovastatin in human plasma.
| | Concentration | RSD (%) | Nominal | Found | Intrarun () | Interrun () |
| NA (μg/mL) | 0.00984 | 0.0101 | 6.0 | 12.7 | 0.246 | 0.237 | 4.2 | 8.3 | 8.86 | 8.71 | 3.7 | 8.5 |
| NAM (μg/mL) | 0.0102 | 0.0103 | 5.5 | 12.0 | 0.254 | 0.271 | 3.5 | 9.3 | 9.14 | 9.58 | 3.2 | 13.5 |
| NUA (μg/mL) | 0.00993 | 0.0103 | 4.8 | 2.0 | 0.248 | 0.268 | 2.3 | 11.3 | 8.94 | 9.52 | 2.3 | 13.0 |
| Lovastatin (ng/mL) | 0.1034 | 0.1051 | 8.2 | 14.9 | 2.585 | 2.688 | 5.0 | 8.6 | 36.19 | 37.09 | 6.6 | 9.7 |
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