Research Article
A Stability Indicating UPLC Method for the Determination of Tramadol Hydrochloride: Application to Pharmaceutical Analysis
Table 5
Method ruggedness.
| | Variable | Mean Peak area ± SD* | %RSD | Mean Rt ± SD* | %RSD | Mean
theoretical
plates ± SD* | %RSD | Mean tailing factor ± SD* | %RSD |
| | Analyte () | 6117724 ± 12676 | 0.21 | 2.005 ± 0.03 | 0.15 | 4076 ± 9634 | 2.36 | 1.03 ± 0.003 | 0.29 |
| | Column () | 6123741 ± 11896 | 0.19 | 2.007 ± 0.04 | 0.20 | 4167 ± 1034 | 2.48 | 1.02 ± 0.002 | 0.20 |
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*Mean value of three determinations
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