Table of Contents
Chromatography Research International
Volume 2012, Article ID 893246, 5 pages
Review Article

Chemometrics in Fingerprinting by Means of Thin Layer Chromatography

Department of Medicinal Chemistry, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland

Received 29 July 2011; Revised 29 September 2011; Accepted 30 September 2011

Academic Editor: Monika Waksmundzka-Hajnos

Copyright © 2012 Łukasz Komsta. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The paper is written as an introductory review, presenting summary of current knowledge about chemometric fingerprinting in the context of TLC, due to a rather small interest in the literature about joining TLC and chemometrics. The paper shortly covers the most important aspects of the chemometric fingerprinting in general, creating the TLC fingerprints, denoising, baseline removal, warping/registering, and chemometric processing itself. References being good candidates as a starting point are given for each topic and processing step.