Table of Contents
Chromatography Research International
Volume 2013, Article ID 242868, 13 pages
http://dx.doi.org/10.1155/2013/242868
Research Article

RP-HPLC Method for Determination of Several NSAIDs and Their Combination Drugs

Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad, Andhra Pradesh 500037, India

Received 29 June 2013; Accepted 13 October 2013

Academic Editor: Andrew Shalliker

Copyright © 2013 Prinesh N. Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. McCarberg and A. Gibofsky, “Need to develop new nonsteroidal anti-inflammatory drug formulations,” Clinical Therapeutics, vol. 34, no. 9, pp. 1954–1963, 2012. View at Google Scholar
  2. D. Kovala-Demertzi, “Recent advances on non-steroidal anti-inflammatory drugs, NSAIDs: organotin complexes of NSAIDs,” Journal of Organometallic Chemistry, vol. 691, no. 8, pp. 1767–1774, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Starek and J. Krzek, “A review of analytical techniques for determination of oxicams, nimesulide and nabumetone,” Talanta, vol. 77, no. 3, pp. 925–942, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Anandakumar, T. Ayyappan, V. Raghu Raman, T. Vetrichelvan, A. S. K. Sankar, and D. Nagavalli, “RP-HPLC analysis of aspirin and clopidogrel bisulphate in combination,” Indian Journal of Pharmaceutical Sciences, vol. 69, no. 4, pp. 597–599, 2007. View at Google Scholar · View at Scopus
  5. H. Senyuva and T. Özden, “Simultaneous high-performance liquid chromatographic determination of paracetamol, phenylephrine HCl, and chlorpheniramine maleate in pharmaceutical dosage forms,” Journal of Chromatographic Science, vol. 40, no. 2, pp. 97–100, 2002. View at Google Scholar · View at Scopus
  6. P. R. Battu, “Simultaneous RP-HPLC determination of nimesulide and paracetamol in tablets,” International Journal of PharmTech Research, vol. 1, no. 3, pp. 514–516, 2009. View at Google Scholar · View at Scopus
  7. H. Chang, W. Ma, and Y. Yang, “HPLC determination of ralated substances of chlophenamine maleate tablets (CPM),” Progress in Modern Biomedicine, 2010. View at Google Scholar
  8. S. S. Chitlange, P. S. Shinde, G. R. Pawbake, and S. B. Wankhede, “Simultaneous estimation of Thiocolchicoside and Aceclofenac in pharmaceutical dosage form by spectrophotometric and LC method,” Der Pharmacia Lettre, vol. 2, pp. 86–93, 2010. View at Google Scholar
  9. D. De Orsi, L. Gagliardi, A. Bolasco, and D. Tonelli, “Simultaneous determination of triprolidine, pseudoephedrine, paracetamol and dextromethorphan by HPLC,” Chromatographia, vol. 43, no. 9-10, pp. 496–500, 1996. View at Google Scholar · View at Scopus
  10. A. P. Dewani, B. B. Barik, S. K. Kanungo, and B. R. Wattyani, “Development and validation of RP-HPLC method for the determination of moxifloxacin in presence of its degradation products,” American-Eurasian Journal of Scientific Research, vol. 6, no. 4, pp. 192–200, 2011. View at Google Scholar
  11. A. M. Di Pietra, R. Gatti, V. Andrisano, and V. Cavrini, “Application of high-performance liquid chromatography with diode-array detection and on-line post-column photochemical derivatization to the determination of analgesics,” Journal of Chromatography A, vol. 729, no. 1-2, pp. 355–361, 1996. View at Publisher · View at Google Scholar · View at Scopus
  12. V. V. Dighe, R. T. Sane, S. N. Menon, H. N. Tambe, S. Pillai, and V. N. Gokarn, “Simultaneous determination of diclofenac sodium and paracetamol in a pharmaceutical preparation and in bulk drug powder by high-performance thin-layer chromatography,” Journal of Planar Chromatography, vol. 19, no. 112, pp. 443–448, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. N. Erk, “Quantitative analysis of chlorpheniramine maleate and phenylephrine hydrochloride in nasal drops by differential-derivative spectrophotometric, zero-crossing first derivative UV spectrophotometric and absorbance ratio methods,” Journal of Pharmaceutical and Biomedical Analysis, vol. 23, no. 6, pp. 1023–1031, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Gandhimathi and T. K. Ravi, “High performance liquid chromatographic determination of aspirin and clopidogrel in tablets,” Indian Journal of Pharmaceutical Sciences, vol. 69, no. 1, pp. 123–125, 2007. View at Google Scholar · View at Scopus
  15. G. Garg and S. Saraf, “Simultaneous estimation of aceclofenac, paracetamol and chlorzoxazone in tablets,” Indian Journal of Pharmaceutical Sciences, vol. 69, no. 5, pp. 692–694, 2007. View at Google Scholar · View at Scopus
  16. V. P. Godse, M. N. Deodhar, A. V. Bhosale et al., “Reverse phase HPLC method for determination of Aceclofenac and Paracetamol in tablet dosage form,” Asian Journal of Research in Chemistry, vol. 2, no. 1, pp. 37–40, 2009. View at Google Scholar
  17. R. Gopinath, S. Rajan, S. N. Meyyanathan, N. Krishnaveni, and B. Suresh, “A RP-HPLC method for simultaneous estimation of paracetamol and aceclofenac in tablets,” Indian Journal of Pharmaceutical Sciences, vol. 69, no. 1, pp. 137–140, 2007. View at Google Scholar · View at Scopus
  18. B. Gowramma, S. Rajan, S. Muralidharan, S. N. Meyyanathan, and B. Suresh, “A validated RP-HPLC method for simultaneous estimation of paracetamol and diclofenac potassium in pharmaceutical formulation,” International Journal of ChemTech Research, vol. 2, no. 1, pp. 676–680, 2010. View at Google Scholar · View at Scopus
  19. V. Das Gupta and A. R. Heble, “Quantitation of acetaminophen, chlorpheniramine maleate, dextromethorphan hydrobromide, and phenylpropanolamine hydrochloride in combination using high-performance liquid chromatography,” Journal of Pharmaceutical Sciences, vol. 73, no. 11, pp. 1553–1556, 1984. View at Google Scholar · View at Scopus
  20. M. A. Haque, M. Shahriar, M. N. Parvin, and S. M. A. Islam, “Validated RP-HPLC method for estimation of ranitidine hydrochloride, domperidone and naproxen in solid dosage form,” Asian Journal of Pharmaceutical Analysis, vol. 3, pp. 59–63, 2011. View at Google Scholar
  21. R. Heydari, “A new HPLC method for the simultaneous determination of acetaminophen, phenylephrine, dextromethorphan and chlorpheniramine in pharmaceutical formulations,” Analytical Letters, vol. 41, no. 6, pp. 965–976, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. S. D. Jadhav, S. R. Butle, S. D. Patil, and P. K. Jagtap, “Validated stability indicating RP-HPLC method for simultaneous determination and in vitro dissolution studies of thiocolchicoside and diclofenac potassium from tablet dosage form,” Arabian Journal of Chemistry, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. D. Jain, R. N. Kachave, and R. N. Bhadane, “Simultaneous estimation of tramadol hydrochloride, paracetamol and domperidone by RP-HPLC in tablet formulation,” Journal of Liquid Chromatography and Related Technologies, vol. 33, no. 6, pp. 786–792, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. R. Joshi and R. Sharma, “Development and validation of RP-HPLC method for simultaneous estimation of three-component tablet formulation containing acetaminophen, chlorzoxazone, and aceclofenac,” Analytical Letters, vol. 41, no. 18, pp. 3297–3308, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Kapil, S. Naik, J. Garima, and N. Mishra, “Spectrophotometric method for simultaneous estimation of paracetamol and domperidone in tablet formulation,” Asian Journal of Research in Chemistry, vol. 2, no. 2, pp. 112–114, 2009. View at Google Scholar
  26. A. Karthik, G. Subramanian, A. Ranjith Kumar, and N. Udupa, “Simultaneous estimation of paracetamol and domperidone in tablets by reverse phase HPLC method,” Indian Journal of Pharmaceutical Sciences, vol. 69, no. 1, pp. 142–144, 2007. View at Google Scholar · View at Scopus
  27. R. D. Kirchhoefer, “Simultaneous determination of aspirin and salicylic acid in bulk aspirin and in plain, buffered, and enteric-coated tablets by high-pressure liquid chromatography with UV and fluorescence detectors,” Journal of Pharmaceutical Sciences, vol. 69, no. 10, pp. 1188–1191, 1980. View at Google Scholar · View at Scopus
  28. E. J. Kubiak and J. W. Munson, “Determination of dextromethorphan hydrobromide by high-performance liquid chromatography using ion-pair formation,” Journal of Pharmaceutical Sciences, vol. 69, no. 12, pp. 1380–1384, 1980. View at Google Scholar · View at Scopus
  29. S. Kumar, A. Joshi, R. S. Thakur, A. K. Pathak, and K. Shah, “Simultaneous estimation of etoricoxib and thiocolchicoside by RP-HPLC method in combined dosage forms,” Acta Poloniae Pharmaceutica, vol. 68, no. 6, pp. 839–843, 2011. View at Google Scholar · View at Scopus
  30. M. Lalitha Devi and K. B. Chandrasekhar, “A validated, specific stability-indicating RP-LC method for moxifloxacin and its related substances,” Chromatographia, vol. 69, no. 9-10, pp. 993–999, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Marín, E. García, A. García, and C. Barbas, “Validation of a HPLC quantification of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations: capsules and sachets,” Journal of Pharmaceutical and Biomedical Analysis, vol. 29, no. 4, pp. 701–714, 2002. View at Publisher · View at Google Scholar · View at Scopus
  32. P. Mishra and A. Dolly, “Simultaneous determination of clopidogrel and aspirin in pharmaceutical dosage forms,” Indian Journal of Pharmaceutical Sciences, vol. 68, no. 3, pp. 365–368, 2006. View at Google Scholar · View at Scopus
  33. A. Mitakos and I. Panderi, “A validated LC method for the determination of clopidogrel in pharmaceutical preparations,” Journal of Pharmaceutical and Biomedical Analysis, vol. 28, no. 3-4, pp. 431–438, 2002. View at Publisher · View at Google Scholar · View at Scopus
  34. M. Momin, P. Yeole, M. Puranik, and S. Wadher, “Reverse phase HPLC method for determination of aceclofenac and paracetamol in tablet dosage form,” Indian Journal of Pharmaceutical Sciences, vol. 68, no. 3, pp. 387–389, 2006. View at Google Scholar · View at Scopus
  35. M. S. Mondal, M. A. Haque, and M. S. Islam, “Development and validation of RP-HPLC method for the simultaneous estimation of domperidone and naproxen in tablet dosage form,” Journal of Applied Pharmaceutical Science, vol. 1, no. 7, pp. 145–148, 2011. View at Google Scholar
  36. I. M. Palabiyik and F. Onur, “The simultaneous determination of phenylephrine hydrochloride, paracetamol, chlorpheniramine maleate and dextromethorphan hydrobromide in pharmaceutical preparations,” Chromatographia, vol. 66, no. 1, pp. S93–S96, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. H. Patel, B. Suhagia, S. Shah, and I. Rathod, “Determination of etoricoxib in pharmaceutical formulations by HPLC method,” Indian Journal of Pharmaceutical Sciences, vol. 69, no. 5, pp. 703–705, 2007. View at Google Scholar · View at Scopus
  38. S. R. Pattan, S. G. Jamdar, R. K. Godge et al., “RP-HPLC method for simultaneous estimation of paracetamol and etoricoxib from bulk and tablets,” Journal of Chemical and Pharmaceutical Research, vol. 1, no. 1, pp. 329–335, 2009. View at Google Scholar
  39. H. Y. Aboul-Enein, H. Hoenen, A. Ghanem, and M. Koll, “Reversed phase liquid chromatographic method for the high-throughput analysis of clopidogrel in pharmaceutical formulations using a monolithic silica column,” Journal of Liquid Chromatography and Related Technologies, vol. 28, no. 9, pp. 1357–1365, 2005. View at Publisher · View at Google Scholar · View at Scopus
  40. V. S. Rajmane, S. V. Gandhi, U. P. Patil, and M. R. Sengar, “High-performance thin-layer chromatographic determination of etoricoxib and thiocolchicoside in combined tablet dosage form,” Journal of AOAC International, vol. 93, no. 3, pp. 783–786, 2010. View at Google Scholar · View at Scopus
  41. K. A. Shaikh and A. B. Devkhile, “Simultaneous determination of aceclofenac, paracetamol, and chlorzoxazone by RP-HPLC in pharmaceutical dosage form,” Journal of Chromatographic Science, vol. 46, no. 7, pp. 649–652, 2008. View at Google Scholar · View at Scopus
  42. P. Shrivastava, P. Basniwal, D. Jain, and S. Shrivastava, “Concurrent estimation of clopidogrel bisulfate and aspirin in tablets by validated RP-HPLC method,” Indian Journal of Pharmaceutical Sciences, vol. 70, no. 5, pp. 667–669, 2008. View at Publisher · View at Google Scholar · View at Scopus
  43. K. B. Singh, S. B. Waikar, and S. P. Padmane, “A validated RP-HPLC method for the simultaneous estimation of paracetamol and naproxen in tablet formulation,” International Journal of Pharmaceutical Sciences and Research, vol. 11, no. 3, pp. 4270–4275, 2012. View at Google Scholar
  44. J. Sippel, L. L. Sfair, E. E. S. Schapoval, and M. Steppe, “New high-performance liquid chromatographic method for determination of clopidogrel in coated tablets,” Journal of AOAC International, vol. 91, no. 1, pp. 67–72, 2008. View at Google Scholar · View at Scopus
  45. P. R. Subbaiah, M. V. Kumudhavalli, C. Saravanan, M. Kumar, and C. R. Margret, “Method development and validation for estimation of Moxifloxacin HCl in tablet dosage form by RP-HPLC method,” Pharmaceutica Analytica Acta, vol. 1, article 109, 2010. View at Google Scholar
  46. N. Sultana, M. S. Arayne, M. Akhtar, S. Shamim, S. Gul, and M. M. Khan, “High-performance liquid chromatography assay for moxifloxacin in bulk, pharmaceutical formulations and serum: application to in-vitro metal interactions,” Journal of the Chinese Chemical Society, vol. 57, no. 4, pp. 708–717, 2010. View at Google Scholar · View at Scopus
  47. S. Sun, G. Liu, and Y. Wang, “Simultaneous determination of acetaminophen, caffeine, and chlorphenamine maleate in paracetamol and chlorphenamine maleate granules,” Chromatographia, vol. 64, no. 11-12, pp. 719–724, 2006. View at Publisher · View at Google Scholar · View at Scopus
  48. L. Suntornsuk, O. Pipitharome, and P. Wilairat, “Simultaneous determination of paracetamol and chlorpheniramine maleate by micellar electrokinetic chromatography,” Journal of Pharmaceutical and Biomedical Analysis, vol. 33, no. 3, pp. 441–449, 2003. View at Publisher · View at Google Scholar · View at Scopus
  49. J. C. Tsao and T. S. Savage, “High-performance liquid chromatographic determination of ibuprofen in bulk drug and tablets,” Drug Development and Industrial Pharmacy, vol. 11, no. 5, pp. 1123–1131, 1985. View at Google Scholar · View at Scopus
  50. M. Varalakshmi, R. J. Vijaya, and K. KrishnaChaitanya, “RP-HPLC method development and validation of domperidone maleate,” International Journal of Pharmaceutical Research and Development, vol. 3, no. 4, pp. 61–64, 2011. View at Google Scholar
  51. A. H. Yadav, L. P. Kothapalli, A. N. Barhate et al., “RP-HPLC method for determination of aceclofenac, chlorzoxazone and paracetamol in bulk and pharmaceutical formulation,” International Journal Pharmaceutical Research Development, vol. 11, p. 7, 2009. View at Google Scholar
  52. N. H. Zawilla, M. Abdul Azim Mohammad, N. M. El Kousy, and S. M. El-Moghazy Aly, “Determination of aceclofenac in bulk and pharmaceutical formulations,” Journal of Pharmaceutical and Biomedical Analysis, vol. 27, no. 1-2, pp. 243–251, 2002. View at Publisher · View at Google Scholar · View at Scopus
  53. T. Hirai, S. Matsumoto, and I. Kishi, “Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction,” Journal of Chromatography B, vol. 692, no. 2, pp. 375–388, 1997. View at Publisher · View at Google Scholar · View at Scopus
  54. F. Lapicque, P. Netter, B. Bannwarth et al., “Identification and simulataneous determination of non-steroidal anti-inflammatory drugs using high-performance liquid chromatography,” Journal of Chromatography, vol. 496, no. 2, pp. 301–320, 1989. View at Publisher · View at Google Scholar · View at Scopus
  55. A. G. Kazemifard and D. E. Moore, “Liquid chromatography with amperometric detection for the determination of non-steroidal anti-inflammatory drugs in plasma,” Journal of Chromatography, vol. 533, pp. 125–132, 1990. View at Publisher · View at Google Scholar · View at Scopus
  56. T. Kosjek, E. Heath, and A. Krbavčič, “Determination of non-steroidal anti-inflammatory drug (NSAIDs) residues in water samples,” Environment International, vol. 31, no. 5, pp. 679–685, 2005. View at Publisher · View at Google Scholar · View at Scopus
  57. G. González, R. Ventura, A. K. Smith, R. De La Torre, and J. Segura, “Detection of non-steroidal anti-inflammatory drugs in equine plasma and urine by gas chromatography-mass spectrometry,” Journal of Chromatography A, vol. 719, no. 1, pp. 251–264, 1996. View at Publisher · View at Google Scholar · View at Scopus
  58. ICH Guidelines: Validation of Analytical Procedures: Text and Methodology, Q2 (R1), 2005.