A Stability Indicating UPLC Method for the Determination of Levofloxacin Hemihydrate in Pharmaceutical Dosage Form: Application to Pharmaceutical Analysis

Table 3

Robustness study.

Conditions	Assay (%)	RT (min)	System suitability data
			Theoretical plates	Asymmetry
Flow mL/min
0.38	98.89	1.27	5244	1.14
0.40	99.08	1.24	5253	1.11
0.42	99.21	1.25	5276	1.10
Column temperature
25°C; 30°C; 35°C	98.93; 99.08; 99.19	1.46; 1.24; 1.14	5378; 5253; 5182	1.12; 1.11; 1.08
ACN: buffer ratio
21 : 79 V/V	99.87	1.40	5402	1.10
23 : 77 V/V	99.08	1.24	5253	1.11
25 : 75 V/V	100.27	1.16	5185	1.13