Simultaneous Quantification of Glibenclamide, Simvastatin, and Quercetin by Using LC-UV Method and Its Application to Pharmacokinetic Study in Rats
Figure 1
LC chromatograms of (a) blank rat plasma, (b) unextracted standards of quercetin (: 5.14 min), nimodipine (: 10.81 min), glibenclamide (: 12.33 min), and simvastatin (: 17.88 min), (c) plasma samples spiked with standards of glibenclamide, simvastatin, and quercetin at a concentration of 500 ng/mL, and (d) plasma sample from a rat 3 h after administration of glibenclamide, simvastatin, and quercetin in combination.
