Research Article
Stress Degradation Studies on Flupirtine Maleate Using Stability-Indicating RP-HPLC Method
Table 5
Robustness of the method (
).
| S. No | Parameter | Modification | Retention time (min) | %RSD |
| (1) | Flow rate | 0.9 mL/min | 3.16 | 0.86 | 1.1 mL/min | 2.84 | 0.97 | (2) | Mobile phase | −5% | 2.97 | 0.72 | +5% | 3.05 | 0.89 | (3) | Temperature | −5°C | 3.11 | 0.40 | +5°C | 3.14 | 0.48 |
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