Stress Degradation Studies on Flupirtine Maleate Using Stability-Indicating RP-HPLC Method

Table 5

Robustness of the method (𝑛=3).

S. No	Parameter	Modification	Retention time (min)	%RSD
(1)	Flow rate	0.9 mL/min	3.16	0.86
		1.1 mL/min	2.84	0.97
(2)	Mobile phase	−5%	2.97	0.72
		+5%	3.05	0.89
(3)	Temperature	−5°C	3.11	0.40
		+5°C	3.14	0.48