Research Article
A Validated New Gradient Stability-Indicating LC Method for the Analysis of Doripenem in Bulk and Injection Formulation
Table 2
Peak purity results of forced degradation studies of drug product.
| Stress condition | % Degradation | Purity angle | Purity threshold | Purity flag |
| Acid stress | 24.0 | 0.549 | 1.638 | No | Base stress | 18.3 | 0.604 | 1.710 | No | Oxidation stress | 23.1 | 0.566 | 1.706 | No | Water stress | 9.7 | 0.783 | 2.461 | No | Photolytic stress | 0.0 | 0.841 | 3.165 | No | Heat stress | 0.3 | 0.874 | 3.224 | No | Humidity stress | 0.2 | 1.066 | 3.068 | No |
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