Research Article
Method Development and Validation for Determination of Febuxostat
from Spiked Human Plasma Using RP-HPLC with UV Detection
Table 3
Results of assessment of accuracy, precision, and %recovery of febuxostat.
| |
Level |
Concentration added (ng/mL) | Intraday () | Interday () |
%Recovery
() | | Mean concentration found (ng/mL) | , % | , % | Mean concentration found (ng/mL) | RE, % | RSD, % |
| | LQC | 500 | 502.41 | 0.48 | 3.17 | 509.46 | 1.88 | 3.49 | 74.34 | | MQC | 2000 | 2070.65 | 0.82 | 3.49 | 1902.32 | −4.88 | 3.34 | 72.13 | | HQC | 7500 | 7640.86 | 1.88 | 4.98 | 7752.68 | 3.37 | 3.17 | 73.98 | | IS | — | — | — | — | — | — | — | 76.13 |
|
|
Relative error; relative standard deviation.
|
