Table of Contents
Chromatography Research International
Volume 2014, Article ID 523184, 5 pages
http://dx.doi.org/10.1155/2014/523184
Research Article

Stability Indicating Liquid Chromatographic Method for Estimation of Trihexyphenidyl Hydrochloride and Risperidone in Tablet Formulation: Development and Validation Consideration

1A. R. College of Pharmacy & G. H. Patel Institute of Pharmacy, Vallabh Vidyanagar, Anand, Gujarat 388120, India
2AUM Research Laboratories, Rakanpur, Gandhinagar 382721, India
3Indukaka Ipcowala College of Pharmacy, New Vallabh Vidyanagar, Anand, Gujarat 388121, India

Received 11 January 2014; Accepted 13 February 2014; Published 19 March 2014

Academic Editor: Toyohide Takeuchi

Copyright © 2014 Patel Bhaumik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. D. Santhosam and S. Kanan, “An HPLC method for the simultaneous estimation of Risperidone and Trihexyphenidyl hydrochloride from bulk and dosage form,” Hygeia Journal for Drug and Medicine, vol. 3, no. 1, pp. 29–33, 2011. View at Google Scholar
  2. D. Patel and J. Patel, “Development and validation of RP-HPLC method for simultaneous estimation of Risperidone and Trihexyphenidyl hydrochloride in tablet dosage forms,” International Journal of Pharmaceutical Sciences Review and Research, vol. 4, no. 3, p. 8, 2010. View at Google Scholar · View at Scopus
  3. V. Rajamanickam, D. Santhosam, D. Sridharan, and A. Thenmozhi, “Simultaneous determination of risperidone and Trihexhyphenidyl hydrochloride from bulk and tablet dosage form by RP-HPLC,” Asian Journal of Research in Chemistry, vol. 3, no. 3, pp. 549–551, 2010. View at Google Scholar
  4. M. F. Seyyed, Z. Afshin, S. Alireza, and K. Arash, “Rapid high performance liquid chromatographic determination of risperidone in human plasma,” Iranian Journal of Pharmaceutical Research, no. 1, pp. 37–40, 2005. View at Google Scholar
  5. Z. R. Dedanla, R. R. Dedanla, N. R. Sheth, J. B. Patel, and B. Patel, “Stability indicating HPLC determination of risperidone in bulk drug and pharmaceutical formulation,” International Journal of Analytical Chemistry, vol. 2011, Article ID 124917, 6 pages, 2011. View at Publisher · View at Google Scholar
  6. S. Bladania, K. K. Bhatt, R. S. Mehta, and D. A. Shah, “RP-HPLC estimation of risperidone in tablet dosage forms,” Indian Journal of Pharmaceutical Sciences, vol. 70, no. 4, pp. 494–497, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. A. P. Suthar, S. A. Dubey, S. R. Patel, and A. M. Shah, “Determination of Risperidone and forced degradation behavior by HPLC in tablet dosage form,” International Journal of PharmTech Research, vol. 1, no. 3, pp. 568–574, 2009. View at Google Scholar · View at Scopus
  8. A. Maślanka, J. Krzek, and A. Patrzałek, “Determination of risperidone in tablets in the presence of its degradation products and placebo-derived constituents,” Acta Poloniae Pharmaceutica—Drug Research, vol. 66, no. 5, pp. 461–470, 2009. View at Google Scholar · View at Scopus
  9. H. Ming-zhu, S. Jian-zhong, C. Jun-chun, L. Jian, and Z. Hui-li, “Determination of risperidone in human plasma by HPLC-MS/MS and its application to a pharmacokinetic study in Chinese volunteers,” Journal of Zhejiang University: Science B, vol. 9, no. 2, pp. 114–120, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. D. G. Rao, S. Kathirvel, and S. V. Satyanarayana, “Development and validation of TLC-densitometry method for the estimation of antipsychotic drug in bulk and tablet formulation,” International Journal of ChemTech Research, vol. 2, no. 4, pp. 2063–2069, 2010. View at Google Scholar · View at Scopus
  11. R. B. Patel, M. R. Patel, K. K. Bhatt, and B. G. Patel, “HPTLc method development and validation for analysis of risperidone in formulations, and in-vitro release study,” Acta Chromatographica, vol. 22, no. 4, pp. 549–567, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. V. Rajamanickam, D. Santhosam, D. Sridharan, and A. Thenmozhi, “Simultaneous determination of Risperidone and Trihexhyphenidyl Hydrochloride from bulk and tablet dosage form by RP-HPLC,” Asian Journal of Research in Chemistry, vol. 3, no. 3, pp. 549–551, 2010. View at Google Scholar
  13. R. B. Patel, M. R. Patel, K. K. Bhatt, and B. G. Patel, “HPTLC method development and validation: quantification of paliperidone in formulations and in vitro release study,” Analytical Methods, vol. 2, no. 5, pp. 525–531, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. M. R. Patel, R. B. Patel, J. R. Parikh, and B. G. Patel, “HPTLC method for estimation of tazarotene in topical gel formulations and in vitro study,” Analytical Methods, vol. 2, no. 3, pp. 275–281, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. R. B. Patel, M. R. Patel, N. Dubey, N. N. Dubey, and B. G. Patel, “HPTLC method development and validation: strategy to minimize methodological failures,” Journal of Food and Drug Analysis, vol. 20, no. 4, pp. 561–571, 2012. View at Google Scholar
  16. ICH Harmonised Tripartite Guideline, Validation of Analytical procedures: Text and Methodology, Q2 (R1), Geneva, Switzerland, 2005, http://www.ich.org.