Chromatography Research International / 2014 / Article / Tab 1

Research Article

Stability Indicating Liquid Chromatographic Method for Estimation of Trihexyphenidyl Hydrochloride and Risperidone in Tablet Formulation: Development and Validation Consideration

Table 1

Summary of HPLC method development and validation.

ParametersData obtained

Theoretical plate
Retention time (min)
Correlation coefficient
Linearity ( )50–175 ( g/mL)50–175 ( g/mL)
Precision (% RSD)
Repeatability ( )0.1810.656
Accuracy (% recovery)99.42–100.26%99.06–100.42%
LOD0.40 ( g/mL)1.24 ( g/mL)
LOQ1.29 ( g/mL)3.92 ( g/mL)

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