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Case Reports in Pathology
Volume 2011, Article ID 514613, 4 pages
Case Report

Acute Demyelination in a Person with Amphetamine Abuse

1Laboratory of Neuropathology, Department of Pathology and Neuropathology, State Neuropsychiatric Hospital Wagner-Jauregg, Wagner-Jauregg-Weg 15, 4020 Linz, Austria
2Institute of Legal Medicine, University of Rostock, 18055 Rostock, Germany

Received 20 June 2011; Accepted 16 August 2011

Academic Editor: P. Tosi

Copyright © 2011 Serge Weis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report the case of a 31-year-old woman, admitted to the hospital for chest pain, dying a few days later from septic multiorgan failure, and showing at autopsy foci of acute demyelination in the occipital lobe. Gas chromatography/mass spectrometry analysis revealed the presence of amphetamine in the demyelinated area, which might be considered as the pathogenic agent, since other causes for demyelination could be excluded. This case represents the first report showing a demyelinating process due to a street drug.