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Case Reports in Pathology
Volume 2011, Article ID 929654, 3 pages
Case Report

Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases

Department of Pathology, JSS Hospital, MG Road, Mysore, Karnataka 570004, India

Received 19 July 2011; Accepted 23 August 2011

Academic Editors: K. Aozasa and P. Kornprat

Copyright © 2011 Vani Krishnamurthy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Carcinosarcoma is a rare tumor composed of variable proportions of carcinomatous and sarcomatous elements and comprises less than one percent of all gallbladder malignancies. In most reported cases of carcinosarcoma of gallbladder, the epithelial component is adenocarcinoma. The mesenchymal component varies from homogenous sarcoma to more heterotopic elements like malignant bone, cartilage, and other mesenchymal tissues. We report a rare case of carcinosarcoma of the gallbladder in an 83-year-old male, with the carcinomatous component represented by undifferentiated carcinoma (spindle and giant cell type with osteoclastic giant cells) and the mesenchymal component seen as foci of chondrosarcoma.