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Case Reports in Pathology
Volume 2012, Article ID 195607, 5 pages
Case Report

Development of Hepatocellular Carcinoma Associated with Anabolic Androgenic Steroid Abuse in a Young Bodybuilder: A Case Report

1Department of Pathology, University Hospital of Cologne, Kerpener Straße 62, 50937 Cologne, Germany
2Department of General Visceral and Cancer Surgery, University Hospital of Cologne, Kerpener Straße 62, 50924 Cologne, Germany

Received 13 February 2012; Accepted 9 April 2012

Academic Editors: A. Rajput, S. Shousha, T. Tot, and D. Tsuruta

Copyright © 2012 Aline Hardt et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and abdominal pain, abdominal ultrasound was performed in a 37-year-old male professional bodybuilder. A hyperechoic lesion in the liver was detected in segment VI. The magnetic resonance imaging showed hepatomegaly and confirmed the lesion, which showed features of a hepatocellular adenoma (HCA). Laboratory values were inconspicuous. After laparoscopic segmentectomy the histological examination revealed HCC. Conclusion. While the development of HCA in the liver by chronic intake of AAS is well known, little is known about the association with HCC. The presented case may indicate aetiological association of chronic intake of AAS and the development of HCC.