Case Report

Malignant Perivascular Epithelioid Cell Tumor of the Esophagus

Table 1

Immunohistochemical profile of the tumor.

AntigenClone and sourceDilutionScore values

MelanosomeHMB45 (Dako, Glostrup, Denmark)Prediluted + +
S100polyclonal (Ventana, Tucson, AZ, USA)Prediluted + +
VimentinV9 (BioGenex, San Ramon, CA, USA)1 : 100 + +
MitfD5 (Dako)1 : 100 + +
Smooth muscle actinHHF35 (Dako)1 : 800 +
DesminD33 (Dako)1 : 50
High molecular weight cytokeratins34betaE12 (Ventana)Prediluted
Low molecular weight cytokeratinsCAM 5.2 (Becton-Dickinson, Mountainview, CA, USA)1 : 10
Intermediate/low-molecular-weight cytokeratinsMNF116 (Dako)1 : 50
CD45 antigenRP2/18 (Ventana)Prediluted
CD99 antigen12E7 (Dako)Prediluted
ChromograninDAK A3 (Dako)1 : 100
bcl-2 oncoprotein124 (Dako)1 : 50
CD20 antigenL26 (Ventana)Prediluted
CD3 antigen2GV6 (Ventana)Prediluted
CD138 antigenB-A38 (Ventana)Prediluted
Kappa chainspolyclonal (Ventana)Prediluted
Lambda chainspolyclonal (Ventana)Prediluted
PDGFRAC-20 (Dako)1 : 100