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Case Reports in Pathology
Volume 2012 (2012), Article ID 471368, 3 pages
Case Report

Pigmented Tumour of the Eyelid with Unexpected Findings

1Department of Ophthalmology, Marienhospital Aachen, Friedrich-Ebert-Allee 98, 52066 Aachen, Germany
2Department of Ophthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127 Bonn, Germany
3Division of Ophthalmic Pathology, Department of Ophthalmology, University of Bonn, Ernst-Abbe-Straße 2, 53127 Bonn, Germany
4University Eye Hospital Bonn, Ernst-Abbe-Straße 2, 53127 Bonn, Germany
5Department of Pathology, University of Bonn, Sigmund-Freud-Straße 25, 53127 Bonn, Germany

Received 29 February 2012; Accepted 12 April 2012

Academic Editors: F. Al-Mulla, M. Halushka, and A. Rajput

Copyright © 2012 Anne C. Hunold et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 63-year-old patient presented with a small painless nodular tumour of his left lower eyelid which had increased in size over the last few weeks. The tumour was excised by wedge resection and submitted for ophthalmopathologic examination. Histopathologic examination revealed a cystic lesion of apocrine origin with focal proliferations. The proliferative cells appeared pleomorphic and displayed marked atypia. Staining with Ki67 revealed a significant mitotic activity supporting the diagnosis of an apocrine adenocarcinoma of Moll. As the lesion displayed in most parts characteristics of a benign apocrine hidrocystoma, a thorough and critical histopathological examination is required in such cases to avoid missing an early malignant transformation.