Primary Leiomyosarcoma of Breast in an Adolescent Girl: A Case Report and Review of the Literature
Figure 1
Gross photographs showing the external aspect (a) and cut surface (b) of the specimen showing a well-circumscribed and encapsulated mass with a thin rim of breast parenchyma surrounding it. The tumor is homogenous, whitish with areas of myxoid change. (c, d, e) Progressive increasing magnification of histology (40x, 100x and 400x) showing the well-encapsulated mass composed of intersecting fascicles of spindle cells with frequent mitoses. (f) Peroxidase-based immunohistochemistry for smooth muscle actin (SMA) showing diffuse, strong cytoplasmic positivity.
