Complex Form Variant of Dysembryoplastic Neuroepithelial Tumor of the Cerebellum

Figure 2

Microscopical findings of the resected tumor. (a) Hamartomatous-hyalinized vessels among the tumor cells can be seen (h and e, ×40). (b) Rosenthal fibers (h and e, ×400). (c) Hyalinized vessels and eosinophilic granular bodies (arrow) (h and e, ×200). (d) Vessels with glomeruloid aspect among tumor cells (h and e, ×100). (e) Strong GFAP expression in the areas with aspect of pilocytic astrocytoma (GFAP, ×200). (f) Area of removed tissue showing normal cerebellar cortex. Some Purkinje cells with abnormal position, and granular cells with normal aspect can be seen (h and e, ×200). (g) Tumor area showing small oligodendroglial-like cells with absence of GFAP positivity (GFAP, ×200). (h) Tumor area with small oligodendroglial-like cells and strong positivity to synaptophysin (×100). (i) Cells with larger size and strong synaptophysin expression can be seen. (×200). (j) and (k) Floating neurons can occasionally observed within microcysts, h and e (j) and synaptophysin expression (k) ×400.