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Case Reports in Pathology
Volume 2012, Article ID 802515, 3 pages
Case Report

Primary Renal Epithelioid Hemangioendothelioma

Department of Pathology, University of Pittsburgh Medical Center, 3550 Terrace Street, A614 Scaife Hall, Pittsburgh, PA 15261, USA

Received 1 August 2012; Accepted 25 September 2012

Academic Editors: M. Guindi, I. Reuter, and D. Vlachodimitropoulos

Copyright © 2012 S. Roy and A. V. Parwani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Epithelioid hemangioendothelioma is a rare vascular tumor with intermediate biologic behavior and metastatic potential. Primary renal epithelioid hemangioendothelioma is extremely rare and we present the second report of this rare tumor in an interesting clinical scenario. A 59-year-old male with established history of widely metastatic high grade esophageal adenocarcinoma was found to have an isolated renal nodule on a followup computed tomography (CT) scan. Surgical excision, with the suspicion of metastatic carcinoma, and subsequent pathologic examination revealed an epithelioid hemangioendothelioma. The various differential diagnoses and use of morphological clues and immunohistochemistry are discussed.