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Case Reports in Pathology
Volume 2012, Article ID 850658, 2 pages
Case Report

Pachyonychia Congenita-Associated Alopecia

Department of Dermatopathology, Tehran University of Medical Sciences, Tehran, Iran

Received 8 July 2012; Accepted 6 September 2012

Academic Editors: J. S. Khurana and P. Kornprat

Copyright © 2012 Azita Nikoo. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 5-year-old female, known case of pachyonychia congenita, presented with diffuse hair loss; remaining hairs were easily plucked kinky hairs. Hair samples from patient were investigated using a light microscope. The hairs of the patients were mainly anagen hairs and unlike normal plucked anagen hairs, showed keratinization and cornification of their hair bulbs. No specific hair shaft abnormality was found.