Case Report

Mucoepidermoid Carcinoma of the Intrapancreatic Common Bile Duct: Immunohistochemical Profile, Prognosis, and Review of the Literature

Figure 2

(a) Nest of mucin-secreting tumor cells, lined by squamoid tumor cells (H&E, 20x). (b) Diffuse CK7 positivity (CK7 stain, 20x). (c) Tumor cells immunoreactive for MUC1 (MUC1 stain, 20x). (d) Glandular luminal mucin-secreting tumor cells focally stained for CK20 (CK20 stain, 20x). (e) MUC4 positivity in the apical aspect of luminal mucin-secreting tumor cells (MUC4 stain, 20x). (f) CEA positivity in glandular luminal tumor cells (CEA stain, 20x). (g) MUC5 staining in the luminal tumor cells (MUC5 stain, 20x). (h) Mucicarmine stain highlighting the intracytoplasmic mucin in the tumor cells (mucicarmine stain, 20x). (i) Outer squamoid tumor cells showed diffuse p63 staining (p63 stain, 20x). (j) Outer squamoid tumor cells showed diffuse CK5/6 staining (CK5/6 stain, 20x).
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(a)
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(b) CK7
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(c) MUC1
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(d) CK20
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(e) MUC4
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(f) CEA
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(g) MUC5
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(h) Mucicarmine
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(i) p63
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(j) CK5/6