Intrathyroidal Parathyroid Carcinoma: Report of an Unusual Case and Review of the Literature

Table 1

Literature review of published intrathyroidal parathyroid carcinoma cases.

Reference	Case no.	Age/sex	Presentation	Tumor location and size	Treatment	Outcome
Ernst et al., 1993 [6]	1	52/F	Hyperparathyroidism/hypercalcemia	Left thyroid, 2.5 cm	Left thyroidectomy	NED, 4 mo
Crescenzo et al., 1998 [7]	2	60/F	Left neck mass, hyperparathyroidism/ hypercalcemia	Left thyroid, 1.5 cm	Left thyroidectomy, isthmusectomy	NED, 18 mo
Kirstein and Ghosh, 2001 [8]	3	74/M	Hyperparathyroidism	Left thyroid, NR	Left thyroidectomy	NR
Schmidt et al., 2002 [9]	4	76/F	Hyperparathyroidism/hypercalcemia	Right superior thyroid, 3.2 cm	Right thyroidectomy, isthmusectomy	NED, 1 yr
Hussein et al., 2006 [10]	5*	63/F	Hyperparathyroidism/hypercalcemia	Left thyroid, 6.0 cm	Left thyroidectomy	NED, >1 mo
Foppiani et al., 2007 [11]	6	67/F	Hyperparathyroidism/hypercalcemia, multinodular goiter	Right inferior thyroid, 3.0 cm	Total thyroidectomy	NED, 5 yr
Herrera-Hernández et al., 2011 [12]	7	14/F	Hyperparathyroidism/hypercalcemia	Right thyroid, 2.5 cm	Right thyroidectomy	NED, 18 mo
Vila Duckworth et al., present case	8	51/F	Hyperparathyroidism/hypercalcemia, thyromegaly	Right superior thyroid, 1.4 cm	Total thyroidectomy	NED, 2.5 yr

NR indicates not reported; NED: no evidence of disease; mo: months; yr: years.
*Case apparently also described by Temmim et al. 2008 [13].