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Case Reports in Pathology
Volume 2013, Article ID 481937, 4 pages
Case Report

Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy

1Department of Anatomic and Molecular Pathology, Lagos University Teaching Hospital, P.M.B. 12003, Lagos State, Nigeria
2Department of Cellular Pathology, Queen’s Hospital, Rom Valley Way, Romford, UK
3Department of Radiodiagnosis, Lagos University Teaching Hospital, Lagos State, Nigeria

Received 23 October 2013; Accepted 5 December 2013

Academic Editors: A. Rajput and A. N. Walker

Copyright © 2013 Orah Nnamdi Obumneme et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. Follicular lymphoma in situ (FLIS) is a recently described entity with few cases recognized worldwide. To our knowledge, this is the first FLIS reported from West Africa. Case Presentation. We present the case of a 48-year-old civil servant with axillary lymphadenopathy discovered on routine mammography. On histology, a predominant reactive change with aggregates of melanophages was seen prompting a diagnosis of reactive lymphadenopathy. Immunohistochemistry done in our laboratory showed CD10 and Bcl-6 positive germinal centres with a small population of Bcl-2 positive germinal centre centre cells that were limited to some of the germinal centres. Conclusion. This highlights the use of immunohistochemistry in lymph node pathology—a resource which is very limited in our environment.