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Case Reports in Pathology
Volume 2013, Article ID 738014, 4 pages
Case Report

Myofibroblastoma of the Female Breast with Admixed but Distinct Foci of Spindle Cell Lipoma: A Case Report

1Department of Histopathology, Laboratory Block, Charing Cross Hospital Campus, Imperial College Healthcare NHS Trust and Imperial College, Fulham Palace Road, London W6 8RF, UK
2Department of Histopathology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt

Received 21 October 2013; Accepted 20 November 2013

Academic Editors: J. Kulka and I. Meattini

Copyright © 2013 Hazem A. H. Ibrahim and Sami Shousha. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Mammary myofibroblastoma (MFB) is a rare benign spindle neoplasm that affects both sexes with a male predominance. It can exhibit a wide range of histological patterns. We report a case of epithelioid/spindle MFB of the female breast with admixed, but distinct, foci of spindle cell lipoma. Whilst all the spindle cells within the tumour expressed CD34, AR, ER, BCL2, and CD10, only those within the myofibroblastoma expressed desmin and only those within the lipomatous areas expressed S100. This finding, to our knowledge, is a novel one that has not been reported before.