A Novel del(20q) in Aggressive Nodal Marginal Zone Lymphoma

Figure 3

FISH and cytogenetics analysis. (A) FISH performed on a touch preparation of representative lymph node tissue shows only one positively tagged 20q12 (red signal) per cell. Control tag 6p11 (green) shows dual positivity. FISH is diagnostic for del(20q12). (FISH probes from Abbott Molecular, Inc.) (B) Karyotype of bone marrow aspirate. Cytogenetics performed on bone marrow tissue reveals deletion of 20q11.2 (arrow).