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Case Reports in Pathology
Volume 2013, Article ID 798435, 3 pages
Case Report

Low-Grade Central Osteosarcoma of the Rib: A Case Report and Brief Review of the Literature

Department of Pathology and Laboratory Medicine, 503 South Jackson Street, Louisville, KY 40202, USA

Received 26 March 2013; Accepted 28 April 2013

Academic Editors: H. Kuwabara, I. Meattini, E. Miele, A. Mima, A. Pich, and S. Shousha

Copyright © 2013 Mana Moghadamfalahi and Houda Alatassi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Low-grade central osteosarcoma is a rare variant of osteosarcoma which comprises less than 1-2% of all osteosarcomas. Most low-grade osteosarcomas involve long bones, most commonly distal femur, and proximal tibia. Histologically this tumor is difficult to diagnose, and an unusual location makes this diagnosis even more challenging. Here we report a case of low-grade osteosarcoma presenting as a chest wall mass involving the left 6th–8th ribs. This unusual site of presentation significantly added to the diagnostic difficulties of this rare tumor with challenging histologic features. To the best of our knowledge, only six cases of low-grade central osteosarcoma of the ribs have been reported in the English literature.