Brooke-Spiegler Syndrome: A Rare Entity

Figure 2

Histology of lesion.

(a) Tumor cells located in dermis (HE 100X)

(b) Jigsaw puzzle appearance (HE 100X)

(c) Peripheral palisading with dark staining cells at periphery and light staining cells in the center (400X)

(d) Cell nests surrounded by hyalinized material (HE 100X)