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Case Reports in Pathology
Volume 2014, Article ID 416170, 3 pages
Case Report

Primary Renal Angiosarcoma with Extensive Necrosis: A Difficult Diagnosis

Department of Pathology, University of Tennessee Health Science Center, Memphis, TN 38163, USA

Received 23 April 2014; Accepted 22 June 2014; Published 15 July 2014

Academic Editor: Katsuyuki Aozasa

Copyright © 2014 Sohail Qayyum et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Angiosarcoma of the kidney is an exceedingly rare and aggressive neoplasm. Very few cases have been reported in the English literature to date. We report a case of primary renal angiosarcoma with extensive necrosis and discuss its diagnostic difficulties. An 86-year-old male presented with a 12 cm necrotic renal mass and multiple pulmonary and hepatic nodules. A CT guided renal biopsy revealed extensive necrosis and few vascular channels lined by malignant endothelial cells. Diagnosis was given on a morphologic base and proven by an immunohistochemical study. Primary renal angiosarcoma should be included among the differential diagnosis of necrotic renal lesions.