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Case Reports in Pathology
Volume 2014 (2014), Article ID 471645, 3 pages
http://dx.doi.org/10.1155/2014/471645
Case Report

Spinal Cord Glioneuronal Tumor with Rosetted Neuropil-Like Islands in Pediatric Age Group

1Department of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University, 34000 Istanbul, Turkey
2Department of Radiology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey

Received 16 October 2014; Accepted 14 November 2014; Published 10 December 2014

Academic Editor: Cheryl Ann Palmer

Copyright © 2014 Nil Comunoglu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Glioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial component was chiefly fibrillary astrocytic, punctuated by neuropil-like islands. Immunohistochemically, glial tissue was GFAP positive, and neuropil-like areas and big neurons were synaptophysin reactive. For astrocytic component Ki-67 proliferation index was 1% and p53 was immunonegative. This case is unique in that in the literature it is the second reported case in pediatric age group that is located at spinal cord.