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Case Reports in Pathology
Volume 2014, Article ID 724895, 3 pages
Case Report

Role of Fine Needle Aspiration in the Diagnosis of the Rare Disease of Langerhans Cell Histiocytosis in a Child

1Mercy Hospital, 800 Myrtle Street, Independence, KS 67301, USA
2Long Island Jewish Health System, 6 Ohio Drive, Lake Success, NY 11040, USA
3Cytopathology, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA

Received 25 September 2013; Accepted 9 December 2013; Published 22 January 2014

Academic Editors: A. A. Ahmed and D. Tsuruta

Copyright © 2014 Seema Lale et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Langerhan’s cell histiocytosis (LCH) results from the proliferation of immunophenotypically and functionally immature, morphologically rounded Langerhan’s cells along with eosinophils, macrophages, lymphocytes, and, commonly, multinucleated giant cells. Here we report a case in a 6-year-old boy of differential diagnoses including dermatopathic lymphadenitis (DL), parasitic infection, Kimura’s disease, hypersensitivity reactions, cat-scratch disease, sinus histiocytosis with massive lymphadenopathy (SHML), hyperplasic lymph nodes, and lymphoma.