Isolated Ocular Manifestation of Relapsed Chronic Myelogenous Leukemia Presenting as Myeloid Blast Crisis in a Patient on Imatinib Therapy: A Case Report and Review of the Literature

<div>Flow cytometric immunophenotypic analysis of vitreous fluid: blast gate (P4 gate in the top line) represents the dim CD45+ cells with low side light scatter (SSC). Blast gate (P3 gate in the bottom line) represents the same population of blasts analyzed for cytoplasmic markers in a separate tube. The distinct cluster of blasts (red color population) exhibit the following immunophenotypic characteristics:<i> positive for</i> CD34, CD117, CD7, CD11b, CD13 (dim), and CD33;<i> negative for</i> CD19, CD10, CD20, CD3, CD5, CD15, CD16, CD61, CD235a, HLA-DR, CD14, cytoplasmic CD3, cytoplasmic CD79a, cytoplasmic MPO, and cytoplasmic TdT.</div>

Case Reports in Pathology

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Figure 4: Isolated Ocular Manifestation of Relapsed Chronic Myelogenous Leukemia Presenting as Myeloid Blast Crisis in a Patient on Imatinib Therapy: A Case Report and Review of the Literature 

Figure 4 | Isolated Ocular Manifestation of Relapsed Chronic Myelogenous Leukemia Presenting as Myeloid Blast Crisis in a Patient on Imatinib Therapy: A Case Report and Review of the Literature 