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Case Reports in Pathology
Volume 2015, Article ID 537297, 4 pages
http://dx.doi.org/10.1155/2015/537297
Case Report

MYC Amplification in Angiosarcoma Arising from an Arteriovenous Graft Site

1Department of Medicine, Section of Dermatology, University of Chicago, 5841 S Maryland Avenue, MC 5067, Chicago, IL 60637, USA
2Department of Medicine, Section of Hematology/Oncology, University of Chicago, 5841 S Maryland Avenue, MC 6092, Chicago, IL 60637, USA
3Department of Pathology, University of Chicago, 5841 S Maryland Avenue, MC 6161, Chicago, IL 60637, USA

Received 1 August 2015; Revised 29 October 2015; Accepted 8 November 2015

Academic Editor: Khin Thway

Copyright © 2015 Kristen M. Paral et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. J. Young, N. J. Brown, M. W. Reed, D. Hughes, and P. J. Woll, “Angiosarcoma,” The Lancet Oncology, vol. 11, no. 10, pp. 983–991, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. Y. A. Qureshi, D. C. Strauss, K. Thway, C. Fisher, and J. M. Thomas, “Angiosarcoma developing in a non-functioning arteriovenous fistula post-renal transplant,” Journal of Surgical Oncology, vol. 101, no. 6, pp. 520–523, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. K. Demey, L.-M. Reyns, and S. Schepers, “Angiosarcoma arising in an arteriovenous fistula in a patient without kidney transplant,” Acta Chirurgica Belgica, vol. 114, no. 1, pp. 75–78, 2014. View at Google Scholar · View at Scopus
  4. M. M. Keane and D. N. Carney, “Angiosarcoma arising from a defunctionalized arteriovenous fistula,” Journal of Urology, vol. 149, no. 2, pp. 364–365, 1993. View at Google Scholar · View at Scopus
  5. N. R. Parrott, P. D. Scott, A. J. Freemont, and R. W. G. Johnson, “Angiosarcoma in an arteriovenous fistula following successful renal transplantation—a case report,” Transplantation, vol. 55, no. 3, pp. 676–677, 1993. View at Google Scholar · View at Scopus
  6. P. J. Conlon Jr., T. Daly, G. Doyle, and M. Carmody, “Angiosarcoma at the site of a ligated arteriovenous fistula in a renal transplant recipient,” Nephrology Dialysis Transplantation, vol. 8, no. 3, pp. 259–262, 1993. View at Google Scholar · View at Scopus
  7. B. M. Wehrli, D. L. Janzen, O. Shokeir, B. A. Masri, S. K. Byrne, and J. X. O'Connell, “Epithelioid angiosarcoma arising in a surgically constructed arteriovenous fistula: a rare complication of chronic immunosuppression in the setting of renal transplantation,” The American Journal of Surgical Pathology, vol. 22, no. 9, pp. 1154–1159, 1998. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Bessis, A. Sotto, P. Roubert, P.-E. Chabrier, G. Mourad, and J.-J. Guilhou, “Endothelin-secreting angiosarcoma occurring at the site of an arteriovenous fistula for haemodialysis in a renal transplant recipient,” British Journal of Dermatology, vol. 138, no. 2, pp. 361–363, 1998. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Farag, J. A. Schulak, F. W. Abdul-Karim, and J. K. Wasman, “Angiosarcoma arising in an arteriovenous fistula site in a renal transplant patient: a case report and literature review,” Clinical Nephrology, vol. 63, no. 5, pp. 408–412, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Chanyaputhipong, D. L. T. Hock, and M. G. Sebastian, “Disseminated angiosarcoma of the dialysis fistula in 2 patients without kidney transplants,” American Journal of Kidney Diseases, vol. 57, no. 6, pp. 917–920, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Webster, L. Wujanto, C. Fisher et al., “Malignancies confined to disused arteriovenous fistulae in renal transplant patients: an important differential diagnosis,” American Journal of Nephrology, vol. 34, no. 1, pp. 42–48, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. C. D. M. Fletcher, J. A. Bridge, P. C. W. Hogendoorn, and F. Mertens, Eds., WHO Classification of Tumours of Soft Tissue and Bone, IARC, Lyon, France, 2013.
  13. S. Ravi and E. L. Chaikof, “Biomaterials for vascular tissue engineering,” Regenerative Medicine, vol. 5, no. 1, pp. 107–120, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. T. G. Moizhess, “Carcinogenesis induced by foreign bodies,” Biochemistry, vol. 73, no. 7, pp. 763–775, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. C. Antonescu, “Malignant vascular tumors—an update,” Modern Pathology, vol. 27, supplement 1, pp. S30–S38, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Guo, L. Zhang, N.-E. Chang, S. Singer, R. G. Maki, and C. R. Antonescu, “Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions,” Genes Chromosomes and Cancer, vol. 50, no. 1, pp. 25–33, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Manner, B. Radlwimmer, P. Hohenberger et al., “MYC high level gene amplification is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema,” The American Journal of Pathology, vol. 176, no. 1, pp. 34–39, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. S. L. J. Verbeke, D. de Jong, F. Bertoni et al., “Array CGH analysis identifies two distinct subgroups of primary angiosarcoma of bone,” Genes Chromosomes and Cancer, vol. 54, no. 2, pp. 72–81, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. W. Shon, W. R. Sukov, S. M. Jenkins, and A. L. Folpe, “MYC amplification and overexpression in primary cutaneous angiosarcoma: a fluorescence in-situ hybridization and immunohistochemical study,” Modern Pathology, vol. 27, no. 4, pp. 509–515, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. C. Y. Lin, J. Lovén, P. B. Rahl et al., “Transcriptional amplification in tumor cells with elevated c-Myc,” Cell, vol. 151, no. 1, pp. 56–67, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. T. A. Jennings, L. Peterson, C. A. Axiotis, G. E. Friedlaender, R. A. Cooke, and J. Rosai, “Angiosarcoma associated with foreign body material: a report of three cases,” Cancer, vol. 62, no. 11, pp. 2436–2444, 1988. View at Publisher · View at Google Scholar · View at Scopus