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Case Reports in Pathology
Volume 2016, Article ID 1280201, 5 pages
http://dx.doi.org/10.1155/2016/1280201
Case Report

Incidentally Detected Kaposi Sarcoma of Adrenal Gland with Anaplastic Features in an HIV Negative Patient

1Pathology Department, Faculty of Medicine, Selçuk University, Alaaddin Keykubat Campus, Selçuklu, 42000 Konya, Turkey
2Pathology Department, Faculty of Medicine, Selçuk University, Turkey
3Clinical Oncology Department, Faculty of Medicine, Selçuk University, Turkey
4Radiology Department, Faculty of Medicine, Selçuk University, Turkey
5Radiation Oncology Department, Faculty of Medicine, Selçuk University, Turkey

Received 15 July 2016; Accepted 8 September 2016

Academic Editor: Atif A. Ahmed

Copyright © 2016 Zeliha Esin Celik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Kaposi sarcoma (KS), a vascular tumor caused by infection with human herpesvirus 8 (HHV8), is a systemic disease that can present with cutaneous lesions with or without visceral involvement. Very few cases of KS, most of which were associated with AIDS, have been reported in the adrenal gland. Anaplastic transformation of KS is a rare clinical presentation known as an aggressive disease with local recurrence and metastatic potential. We report here a 47-year-old HIV negative male presented with extra-adrenal symptoms and had an incidentally detected anaplastic adrenal KS exhibited aggressive clinical course. To the best of our knowledge, this is the first case of anaplastic primary adrenal KS without mucocutaneous involvement but subsequently developed other side adrenal metastases in an HIV negative patient.