Metastatic Gastrointestinal Adenocarcinoma with Osteoblastic Activity: A Case Report of Esophageal and Colonic Primaries

Figure 3

Case 2 histologic features of the sigmoid colon mass, lymph node, and liver masses. (a) CT scan of the abdomen demonstrated liver metastases with marked calcifications within the lesion (red arrow). (b) Left hemicolectomy of the sigmoid colon mass demonstrated moderately differentiated infiltrating neoplastic glands within ulcerated colonic mucosa consistent with primary colonic adenocarcinoma with associated calcifications (H&E, 40x). (c) Resection of lymph node showed foci of metastatic neoplastic glandular cells of colonic primary with associated osteoblastic activity demonstrated by bone formation and calcifications (H&E, 100x). (d) Resections of the liver masses highlighted metastatic neoplastic glands of colonic primary with associated osteoblastic activity demonstrated by calcifications (H&E, 40x).

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