Localized Castleman’s Disease in the Breast in a Young Woman

Figure 2

(a) Histology of the tissue showed proliferation of lymphoid follicles (H&E, 20x). (b) Lymph node with lymphoid cells in an “onion skin” pattern with a hyaline center (H&E, 40x). (c–f) Immunohistochemical staining for CD20, CD3, CD10, and CD21 positivity demonstrated follicular hyperplasia.

(a)

(b)

(c)

(d)

(e)

(f)