A Previously Undescribed Presentation of Mixed Adenoneuroendocrine Carcinoma

Figure 4

Metastasis to the perigastric lymph nodes: (a) CK7 and (b) CK20 images highlight differential staining with strong staining in the glandular component but lack of staining in the neuroendocrine component (a and b, 40x). (c) The glandular elements have a higher proliferation rate than the neuroendocrine on Ki-67 (MIB, 40x). (d) Synaptophysin is diffusely positive in the neuroendocrine but negative in the glandular foci (100x); chromogranin stain had a similar pattern.

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