Paravertebral Well-Differentiated Liposarcoma with Low-Grade Osteosarcomatous Component: Case Report with 11-Year Follow-Up, Radiological, Pathological, and Genetic Data, and Literature Review

Figure 3

Histological features of the different occurrences of the tumor. (a) Well-differentiated liposarcoma component, first occurrence. Lipogenic clusters are entrapped within a stromal proliferation composed of fusiform cells. A cluster of bone formation is obvious. (b) Low-grade osteosarcoma component, first occurrence. The osteogenic areas are composed of long trabeculae of woven bone associated with the same proliferation of fusiform stromal cells in the intertrabecular spaces. These stromal cells are fusiform, elongated with moderate nuclear atypias. These morphological findings are very similar to low-grade osteosarcoma. (c) and (d) Histological aspects of the recurrences. The 2011 recurrence (c) and the 2014 recurrence (d) showed very similar histological findings compared to the first occurrence of the tumor.

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