Nodular Lymphocyte Predominant Hodgkin Lymphoma of the Ileum

Figure 4

Immunohistochemical features of the neoplastic cells. (a) High-power image of a CD20 immunohistochemical stain shows expression by the scattered large neoplastic cells. Numerous small B-cells in the background also are positive. (b) A PAX5 stain also shows positivity in the large neoplastic cells and small background B-cells. (c) An OCT2 stain shows strong nuclear staining in the neoplastic cells. (d) A PD-1 stain shows rosetting of the large neoplastic cells by small PD-1-positive T lymphocytes.

(a)

(b)

(c)

(d)