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Case Reports in Pathology
Volume 2017, Article ID 7949361, 6 pages
Case Report

Two Different Cell Populations Is an Important Clue for Diagnosis of Primary Cutaneous Adenoid Cystic Carcinoma: Immunohistochemical Study

1Pathology Department, Abdurrahman Yurtaslan Oncology Education and Research Hospital, Ankara, Turkey
2Department of Pathology, Numune Education and Research Hospital, Ankara, Turkey

Correspondence should be addressed to Onder Bozdogan; moc.liamtoh@40aplpu

Received 25 September 2016; Accepted 8 December 2016; Published 24 January 2017

Academic Editor: Tibor Tot

Copyright © 2017 Banu Ince Alkan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary cutaneous adenoid cystic carcinoma (PCACC) is a very rare malignancy. The differential diagnosis of PCACCs in pathology practice can be difficult and a group of primary and metastatic lesions, including adenoid basal cell carcinoma of the skin, should be considered in the differential diagnosis. Besides histomorphological clues, immunohistochemistry studies are very helpful in the differential diagnosis of PCACC. We report herein a case of PCACC with extensive immunohistochemical studies and review the literature from an immunohistochemistry perspective.