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Case Reports in Pathology
Volume 2018, Article ID 9486064, 4 pages
https://doi.org/10.1155/2018/9486064
Case Report

Suprasellar Ganglioglioma: Expanding the Differential Diagnosis

1Department of Pathology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USA
2Department of Neurology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USA
3Department of Radiology, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USA
4Department of Medicine, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USA
5Department of Neurosurgery, Augusta University-Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912-3600, USA

Correspondence should be addressed to Amyn M. Rojiani; ude.atsugua@inaijora

Received 6 November 2017; Accepted 31 December 2017; Published 1 February 2018

Academic Editor: Piero Tosi

Copyright © 2018 Isabella Tondi Resta et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This case study describes a young man with symptoms suggestive of the presence of a space-occupying lesion within the cranial cavity. Imaging studies confirmed a lesion in the suprasellar region and surgical intervention to remove the tumor yielded an unexpected diagnosis. Neuroimaging characteristics and histopathology including immunohistochemistry are described. Gangliogliomas are uncommon CNS neoplasms and are most commonly found in the temporal and frontal lobes of young, male adults. They are rarely seen in the suprasellar region and only a handful of cases have been reported to date. The differential diagnoses associated with these suprasellar region lesions can be dependent on the age of the patient and neuroimaging characteristics. The present report highlights the importance of histopathological examination and the need to consider a wide range of diagnostic entities in the differential diagnosis of lesions in this topographic distribution, including rarely encountered tumors such as gangliogliomas.