Superficial Myofibroblastoma in the Vulva Mimicking Aggressive Angiomyxoma: A Case Report and Review of the Literature

Table 2

Pathological features of SMF and other mesenchymal tumors.

(a)

	Histological features
Superficial myofibroblastoma; (SMF)	Usually moderate, sometimes hypocellularity; Fine and dense collagen in stroma; Small to medium-sized dilated vessels, often centrally located
Cellular angiofibroma,	Moderate cellularity; Wispy collagen stroma; Medium-sized vessels, often with hyalinized walls
Mammary type myofibroblastoma,	Moderate to hypercellularity; Thick collagen bundle in stroma, adipose tissues may be present; Blood vessels are not prominent
Angiomyofibroblastoma,; (AMF)	Alternating zones of hyper- and hypocellularity.; Loose texture, contains mast cells in stroma, adipose tissues may be present; Small to medium-sized capillary-like vessels around which epithelioid stroma cells are clustered
Aggressive angiomyxoma; (AA)	Hypocellularity; Myxoid stroma, entrapped tissue may be present; Numerous blood vessels varying from small size to large size with thick muscular walls

(b)

	ER	PgR	Desmin	SMA	CD34
Superficial myofibroblastoma	80-100%; (+)	80-100%; (+)	75-100%; (+)	0-45%; (+)	50-85%; (+)
Cellular angiofibroma	variable expression	variable expression	variable expression	variable expression	variable expression
Mammary-type myofibroblastoma	ND	ND	usually; expressed	variable; expression	usually; expressed
Angiomyofibro; -blastoma	usually expressed	usually expressed	usually expressed	less common	less common
Aggressive angiomyxoma	(+)	(+)	(+)	variable expression	variable; expression