Case Report
An Unusual Hybrid Salivary Gland Tumor: Molecular Analysis Informs the Potential Pathogenesis of This Rare Neoplasm
Table 1
Gene alterations in BCA and MEC components.
| | BCA | MEC |
| Genomic alterations | CREBBP (Q355fs12) | | | GNAS (Q227L) | | | | BAP1 (S489fs82) |
| Variants of unknown significance | CIC (A851V) rs45596843 | CIC (A851V) rs45596843 | | FGF3 (T79M) rs376992420 | FGF3 (T79M) rs376992420 | | MCL1 (M120V) rs151065075 | MCL1 (M120V) rs151065075 | | RAF1 (V312A) rs370243307 PBRM1 | RAF1 (V312A) rs370243307 PBRM1 | | | EPHA7 | | | FUBP1 |
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Abbreviations: BCA, basal cell adenoma; MEC, mucoepidermoid carcinoma; rs, reference sequence. Symbols: text, predicted benign; text, possible sequencing artifacts. |