An Exceptional Case of Liver-Restricted High-Grade B-Cell Lymphoma in a Patient with Clinical History of HBV and HCV Coinfections

Figure 1

Broad fibrous bands separate nodules of necrotic hepatic parenchyma in the setting of cirrhosis (a) and diffuse infiltration of hepatic parenchyma by lymphoma cells admixed with nonneoplastic lymphocytes (b) (H&E); CD10 (c), CD20 (d), and BCL-6 (e) immunostains are strongly and diffusely positive in lymphoma cells; Ki-67 (f) shows a high proliferative index of nearly 100% in malignant cells, which are admixed with nonneoplastic lymphocytes.

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