Renal Tubular Dysgenesis in a Case of Fetus Acardius Amorphus

Figure 1

(a) Photographs of the Fetus acardius amorphus. Fetus acardius amorphus shown as a rounded ovoid mass with a small pedicle symbolizing the umbilical cord. On one surface there exists a colloidal mass, as well as a short pedicle with little hair on it. (b) The Center of Fetus acardius amorphus illustrates an organized bone structure predicted to be the vertebra column, surrounded by yellowish tissue as well as red masses. (c1 and c2) Facitron X-ray analysis of the skeletal system of the Fetus acardius amorphus. The Fetus acardius amorphus shows a complete organized vertebral column, with a rudimentary rib cage and an ovoid bone structure (white arrow) without axial organization of a head, limbs or cranial-caudal poles. (d1 and d2) CISH analysis of interphase cells within paraffin sections of male gonadal tissue using the CEN X/Y Probe. CEN X/Y Probe hybridizes on regular male interphase cells demonstrated by one red (chromosome X) and one green (chromosome Y) signal per nucleus. The Fetus acardius amorphus shows a male XY genotype. Scale bar = 20 μm (D1), scale bar = 5 μm (D2).