Osteosarcomatous Divergence in Dedifferentiated Liposarcoma Presenting as a Colonic Mass

Figure 3

(a) Cellular high-grade nonlipogenic sarcoma component composed of spindle and pleomorphic tumor cells (100X). (b) Focal transition into a well-differentiated liposarcoma with atypical stromal cells (100X). (c, d) Nonlipogenic sarcoma with osteoid matrix and highly atypical cells, resembling a high-grade osteosarcoma (100X). (e) Immunohistochemical staining for SATB2 is positive in osteoblastic cells and intervening atypical cells. (f) Areas of thick interconnected trabeculae of immature woven bone lacking osteoblastic rimming (40X).

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