Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival

Table 1

Reported cases of benign, atypical, and malignant granular cell tumor of the abdominal wall.

No	Authors	Age	Gender	Size Cm.	Type	Location in Abdominal Wall	Metastasis, outcome and remarks
	Year. (Reference)
1	Cave et al Case 3; 1955 [13]	6.5	Female	2	Benign	Dermis and subcutaneous	Not applicable. Patient had one tumor in right submental area of head and one tumor in the abdominal wall.
2	Baraf and Bender Case 1; 1964 [14]	29	Male	0.5-2.5	Benign	Dermis and subcutaneous	Not applicable. Patient had multiple cutaneous GCTs (21 tumors) at various sites including abdominal wall
3	Baraf and Bender Case 2; 1964 [14]	18	Male	0.5-3	Benign	Dermis and subcutaneous	Not applicable. Patient had multiple cutaneous GCTs (15 tumors) at various sites, including abdominal wall.
4	Baraf and Bender Case 3; 1964 [14]	33	Male	0.5-1.5	Benign	Dermis and subcutaneous	Not applicable. Patient had multiple cutaneous GCTs (about 40 tumors) within ten years at various sites
5	Gorelkin et al.; 1978 [15]	58	Female	8	Benign	Intramuscular	Not applicable
6	Apisarnthanarax Case 6; 1981 [16]	43	Female	3	Benign	Subcutaneous	Not applicable
7	Apisarnthanarax Case 7; 1981 [16]	36	Female	2.5	Benign	Subcutaneous	Not applicable
8	Kucan et al; 1982 [17]	8	Male	Small. Size not stated	Benign	Dermis and Subcutaneous	Not applicable. Patient had multiple [18] GCTs of the skin in trunk, upper and lower extremities, and buttocks
9	Geisinger et al.; 1985 [19]	69	Female	Not stated	Malignant	Not stated	Metastases to lungs and lymph nodes. Dead of disease at 96 months post diagnosis.
10	Rifkin et al. Case 1; Mother; 1986 [20]	23	Female	Not stated	Benign	Subcutaneous	Not applicable. Patient had total of 57 cutaneous GCTs excised during 13-year period from age 10 to 23 years at various sites including abdominal wall
11	Rifkin et al. Case 2; Son; 1986 [20]	6	Male	Not stated	Benign	Subcutaneous	Not applicable. Patient had tracheal GCT with a recurrence, two abdominal wall tumors and a perianal tumor
12	Rubenstein et al Case 1; 1987 [21]	7	Female	3	Benign	Subcutaneous	Not applicable. Patient had multiple [11] subcutaneous GCTs in fingers, arms, neck, buttock, abdominal wall, and the largest involved the clitoris (4.5x5.5 cm)
13	Khansur et al; 1987 [22]	Not given	Male	Not stated	Malignant	Not stated	Presented with systemic metastasis in the liver and lung which rapidly progressed and caused death in five months. Son had MGCT of chest wall.
14	Vamsy et al.; 1992 [23]	30	Female	10x8x5	Malignant	Intramuscular	None. Alive at 24 months postop.
15	Menaker and Sanger; 1997 [24]	50	Female	4x2x2	Atypical (Uncertain Malignant Potential)	Subcutaneous	Underwent wide local excision. No recurrence or metastasis at 16 months postop.
16	Fanburg-Smith et al. Case 7; 1998 [9]	32	Male	5.5	Malignant	Attached to rectus muscle sheath	No recurrences or metastasis. Alive at 2 years postop.
17	Fanburg-Smith et al. Case 17; 1998 [9]	49	Female	11	Malignant	Not stated	No recurrence or metastasis. Alive at 7 years postop.
18	Joshi and Aqel 2003 [25]	37	Male	2x1.6	Benign	Intramuscular	Not applicable
19	Chelly et al.; 2005 [18]	67	Female	6x4x3	Malignant	Subcutaneous and intra-muscular	None. Patient died due to pulmonary embolism three months postop.
20	An et al.; 2007 [26]	44	Female	4	Benign	Intramuscular	Not applicable
21	Chaudhry et al; 2008 [27]	70	Female	10	Benign	Intramuscular	Not applicable. Alive and well 5 months postop.
22	Panunzi et al.; 2012 [28]	29	Female	1.5	Benign	Adherent to muscle	Not applicable
23	Chen et al.; 2012 [29]	56	Female	6x3.3	Malignant	Subcutaneous with multiple recurrences	Initial abdominal wall tumor in 2003. Multiple recurrences in 2004, 2006, 2007 and 2009. Mets to right breast and axillary lymph nodes. All resected.; Alive 27 months postop.
24	Toelen et al.; 2013 [30]	68	Female	3	Benign	Subcutaneous	Not Applicable
25	Porta et al.; 2015 [31]	45	Female	3	Benign	Intramuscular	Not Applicable
26	Liu et al.; 2015 [32]	66	Male	3x2.8	Malignant	Dermis and Subcutaneous	No recurrence or metastasis at 12 months postop.
27	Yoon et al.; 2016 [33]	66	Male	4.5x3.4x3	Malignant	Intramuscular	No metastasis or recurrence at 30 months.
28	Imanishi et al. Case 13; 2016 [34]	48	Male	8	Malignant	Not stated	Local recurrence at 27 months. Mets to lung and bone at 26 months.; Died at 87 months postop.
29	Alnashwan et al. Current case; 2019	50	Female	7x6	Malignant	Subcutaneous	Metastases to both lungs and right inguinal lymph node. Alive at 132 months postop.