Multifocal Medulloblastoma in an Adult Patient: Description of a Rare Presentation and Review of the Literature

Figure 2

Histological aspects of the two excised lesions. (a) The right hemispherical lesion made of highly cellular nodules composed of fusiform hyperchromatic cells set in an intervening highly cellular background (haematoxylin and eosin stain, HE; original magnification x10). (b) Nodules are reticulin-free; internodular areas are reticulin-rich (reticulin stain, original magnification x10). (c, d) Areas of anaplasia with highly pleomorphic cells with numerous mitosis and foci of necrosis are present (haematoxylin and eosin stain, HE; original magnification x40 (c), x20 (d)). (e) The paravermian left lesion consisted of expanded nodules made of small cells (haematoxylin and eosin stain, HE; original magnification x10). (f) Expanded nodules are reticulin-free, surrounded by reticulin-rich interlobular areas (reticulin stain, original magnification x10).

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